Levitra shows fastest ever response time demonstrated of any PDE5 treatment tor erectile dysfunction
Treatment with Levitra can result in an erection in just 10 minutes in some men and in most men within 25 minutes. A new clinical study that measured the speed with which men with ED can achieve an erection demonstrated that Levitra has the most rapid onset to date of any PDE-5 inhibitor on the market. The study will be presented at the 7th European Federation of Sexology (EFS) congress in Brighton this week.
The study (called ONTIME – ONseT of Vardenafil In Men with Erectile Dysfunction), presented in the UK, showed that Levitra had a statistically significant response superior to placebo at 10 and 11 minutes with 10 mg and 20 mg doses, respectively. The ONTIME study assessed the earliest time elapsed from dosing to attainment of an erection adequate for penetration leading to completion of successful intercourse (as measured by SEP3 ).
“The results of the ONTIME study show Levitra demonstrated the fastest onset of action to date, meaning men can be confident and engage in a satisfying sexual experience when they want to,” says Professor Francesco Montorsi, study investigator and Associate Professor of Urology at the Universita’ Vita Salute San Raffaele in Milan.
In another study presented at the congress, speed of action was an essential attribute of ED treatment, more so than duration, according to the largest published survey of male sexuality (Men’s Attitudes to Life Events and Sexuality [MALES]). This study found that in men with ED, rapid onset was considered important irrespective of age, while long duration of action became less important as men aged.
“The combined results of these studies demonstrate that men value a rapid onset of action and that Levitra offers patients what they want,” concluded Professor Montorsi.
The MALES study included interviews with 2912 men, aged 20-75, from 8 countries (UK, US, Germany, France, Italy, Spain, Mexico and Brazil).
The ONTIME study was conducted in 724 patients in 80 centres in Europe and North America (8 countries). It was a randomised, double blind, parallel group, multicentre trial, which studied men with ED (baseline IIEF-EF score of 13.0 [moderate severity], ITT population ). The study design included a four-week unmedicated run-in period, followed by a four-week treatment with Levitra 10 mg, 20 mg or placebo, taken on demand. The first four doses were used to determine the earliest time of onset.
In the ONTIME study, the most common drug-related adverse events were generally mild to moderate and included headache, flushing, rhinitis and dyspepsia.
Erectile dysfunction (ED) is defined as the consistent or recurrent inability of a man to attain and/or maintain a penile erection sufficient for sexual performance. 2
It is estimated that some degree of ED affects more than one half of all men over the age of 40 and that worldwide an estimated 152 million men suffer from ED. The number of men with ED is expected to more than double to 322 million by 2025. 3,4 , Despite the high prevalence of sexual dysfunction, experts estimate that only 15-20 percent of men with ED are currently treated. 5
Phosphodiesterase type 5 (PDE-5) is the predominant enzyme found in human penile erectile tissue and is associated with erections. PDE-5 inhibitors typically work by blocking this enzyme to enhance or prolong the erectile response.
Levitra was specifically selected for development as an ED therapy because of its in vitro potency and high selectivity for the inhibition of the PDE-5 enzyme.
Levitra 5, 10 and 20 mg doses are contraindicated in men taking nitrates and nitric oxide donors (a group of medications used to treat angina pectoris, or chest pain), in men concomitantly using HIV protease inhibitors (such as indinavir and ritonavir), and in patients with a known hypersensitivity to any component of the tablet. Please refer to individual country labels for other important prescriber information.
Levitra, researched and discovered by Bayer AG, is marketed by Bayer and GlaxoSmithKline plc (GSK) through a worldwide co-promotion and co-development agreement. Levitra was approved on 6 March 2003 by the European Commission based on the quality, safety and efficacy data submitted. These data included results from more than 3,750 men representing a broad patient population. The US Food and Drug Administration (FDA) approved Levitra for the treatment of ED on 19 August 2003.
The best idea to use Levitra for sexual dysfunction treatment
We all know that the life of a common person has become so busy. Women remain busy in their house works while men remain busy at their job. Both do not have the time to go to doctor for their regular treatment. Even they do not have enough time to spend it with their family. Since they do not spend some of their previous time with their family that is why they are always complained by them. It is high suggested to such busy people that they should manage their time in such a way that they can spend some time with their family members. This thing will definitely increase their love for you. Since their busy schedule does not allow the common man to visit the doctor’s clinic and then having a complete medical checkup so sometimes they become the victim of many health diseases. This article will give you knowledge about the importance of Vardenafil for the treatment of impotent man.
Well, Vardenafil is a medicine and it is the generic name of Levitra. Both medicines are same so you do not be confused while purchasing it. The name doctor will suggest may be Vardenafil or Levitra. It is being sold at NCAAA in three different doses like 2,5mg, 5 mg, 10 mg and 20 mg. These three doses are very lower in capacity so they will not cause any severe problem for your health. Let us discuss about the impotent person. An impotent person is one who cannot get erection when he is sexually excited like a normal man. The main reason of its inactivity is the lower blood flow through blood vessels all the time. It is a biological fact that the blood flow through blood vessels starts to increase when the person thinks about the sexual activity. This thing gives him erection and prepares him to have sex with his partner. Since the impotent person cannot get erection so it becomes difficult for that man to have sex. What he can do if is facing this situation? There is big and good news for the man that the treatment of this sexual problem is available. No surgical or other type of dangerous treatment is required for this purpose. The impotent just need to take Levitra before having sexual intercourse. When he will take Levitra before sex, this medicine will give a rise to the blood flow rate and will ultimately make the penis erect and hard necessary for sex.
Now it is time to learn some things about the use of Levitra. Doctors never suggest using Levitra when they come to know that you are using nitrates in the form of heart diseases treatment. Nitrate is a chemical and Levitra is also contains those chemicals which can destroy your health in a few weeks if it is taken along with nitrate drugs. Levitra is also taken with care when you are suffering with high blood pressure, diabetes and depression.